Of all 31,109 verses in 1,189 chapters in 66 books of the Bible, this is the least important verse, so you can ignore it.
Just kidding! Sorry for the clickbait title and opening line. I hate to disappoint you. There are no unimportant verses in the Bible. And, you can’t ignore any of them. If you have been tempted to ignore any part of the Bible, please don’t ignore the following verses:
Then Jesus was led up by the Spirit into the wilderness to be tempted by the devil. When he had fasted forty days and forty nights, he was hungry afterward. The tempter came and said to him, “If you are the Son of God, command that these stones become bread.” But he answered, “It is written, ‘Man shall not live by bread alone, but by every word that proceeds out of the mouth of God.'” (Matthew 4:1-4 WEB)
“You search the Scriptures, because you think that in them you have eternal life; and these are they which testify about me. (John 5:39 WEB)
Seeing you have purified your souls in your obedience to the truth through the Spirit in sincere brotherly affection, love one another from the heart fervently: having been born again, not of corruptible seed, but of incorruptible, through the word of God, which lives and remains forever. For, “All flesh is like grass, and all of man’s glory like the flower in the grass. The grass withers, and its flower falls; but the Lord’s word endures forever.” This is the word of Good News which was preached to you. (1 Peter 1:22-25 WEB)
Did the word of God originate with you? Or are you the only ones it has reached? If anyone considers himself a prophet or spiritual person, let him acknowledge that what I am writing you is the Lord’s command. But if anyone ignores this, he himself will be ignored. (1 Corinthians 14:36-38 BSB)
For the word of God is living, and active, and sharper than any two-edged sword, and piercing even to the dividing of soul and spirit, of both joints and marrow, and is able to discern the thoughts and intentions of the heart. There is no creature that is hidden from his sight, but all things are naked and laid open before the eyes of him with whom we have to do. (Hebrews 4:12-13 WEB)
There is a blessing for heeding every verse in the Bible
How can a young man keep his way pure?
By living according to your word.
With my whole heart, I have sought you.
Don’t let me wander from your commandments.
I have hidden your word in my heart,
that I might not sin against you. (Psalm 119:9-11 WEB)
Read the context of 1 Thessalonians to get the full impact of these 2 verses. If you heed every verse and don’t ignore any verse, you will be blessed.
And we continually thank God that in receiving the word of God from us, you did not accept it as the word of men, but as the true word of God–the word now at work in you who believe. (1 Thessalonians 2:13)
Now may the God of peace Himself sanctify you completely, and may your entire spirit, soul, and body be kept blameless at the coming of our Lord Jesus Christ. (1 Thessalonians 5:23)
For you have been born again, not of perishable seed, but of imperishable, through the living and enduring word of God. (1 Peter 1:23)
If you ignore any verse in the Bible, it will lead to peril
The Pharisees wanted to be able to concentrate on some verses and ignore other verses so they asked Jesus to justify their opinion. It didn’t go well for them. Don’t fall into their same trap. Don’t ignore any verses.
But the Pharisees, when they heard that he had silenced the Sadducees, gathered themselves together. One of them, a lawyer, asked him a question, testing him. “Teacher, which is the greatest commandment in the law?” Jesus said to him, “‘You shall love the Lord your God with all your heart, with all your soul, and with all your mind.’ This is the first and great commandment. A second likewise is this, ‘You shall love your neighbor as yourself.’ The whole law and the prophets depend on these two commandments.” (Matthew 22:34-40 WEB; Deuteronomy 6:1-19; Mark 12:28-34)
Is not My word like fire, declares the LORD, and like a hammer that smashes a rock?” (Jeremiah 23:29)
There is a judge for the one who rejects Me and does not receive My words: The word that I have spoken will judge him on the last day. (John 12:48)
He said, ‘I ask you therefore, father, that you would send him to my father’s house; for I have five brothers, that he may testify to them, so they won’t also come into this place of torment.’
“But Abraham said to him, ‘They have Moses and the prophets. Let them listen to them.’
“He said, ‘No, father Abraham, but if one goes to them from the dead, they will repent.’
“He said to him, ‘If they don’t listen to Moses and the prophets, neither will they be persuaded if one rises from the dead.'” (Luke 16:27-31 WEB)
Therefore, beloved, seeing that you look for these things, be diligent to be found in peace, without blemish and blameless in his sight. Regard the patience of our Lord as salvation; even as our beloved brother Paul also, according to the wisdom given to him, wrote to you; as also in all of his letters, speaking in them of these things. In those, there are some things that are hard to understand, which the ignorant and unsettled twist, as they also do to the other Scriptures, to their own destruction. You therefore, beloved, knowing these things beforehand, beware, lest being carried away with the error of the wicked, you fall from your own steadfastness. But grow in the grace and knowledge of our Lord and Savior Jesus Christ. To him be the glory both now and forever. Amen. (2 Peter 3:14-18 WEB)